Impact of RNA-Based Viral Infections on Liver Enzyme Profiles in Chronic Liver Disease Patients
DOI:
https://doi.org/10.66238/jaeee14Keywords:
Hepatitis C Virus (HCV), Hepatitis E Virus (HEV), Liver Enzymes, ALT, BiomarkersAbstract
Chronic liver diseases (CLDs) associated with RNA-based viral infections, particularly Hepatitis C Virus (HCV) and Hepatitis E Virus (HEV), exhibit diverse biochemical profiles that can reflect both the severity of hepatic injury and the nature of the viral insult. This study investigates the differential impact of HCV and HEV on liver enzyme markers in CLD patients, focusing on transaminases, cholestatic markers, and synthetic function indicators. Through quantitative analysis of serum ALT, AST, ALP, GGT, bilirubin, albumin, and INR, alongside viral RNA load, we demonstrate that HCV patients typically present with elevated ALT levels compared to HEV patients, while cholestatic markers such as ALP and GGT show moderate elevations in both groups. These findings provide critical insights into hepatic dysfunction patterns and underscore the role of liver enzymes as non-invasive markers for disease monitoring and therapeutic guidance in viral hepatitis.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Carlos M. Navarro
This work is licensed under a Creative Commons Attribution 4.0 International License.
All articles published in the Journal of Advanced Electrical and Electronic Engineering (JAEEE) are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). Authors retain copyright of their work while granting the journal the right of first publication.
Under this license, users are permitted to read, download, copy, distribute, print, share, adapt, and reuse published material for both commercial and non-commercial purposes, provided appropriate credit is given to the original author(s), the source of publication is acknowledged, a link to the license is provided, and any changes made are clearly indicated.
The license does not permit users to imply endorsement by the original authors or the journal. No additional restrictions may be imposed that prevent others from exercising the rights granted under CC BY 4.0.
By submitting to the journal, authors confirm that their work is original, does not infringe upon third-party rights, and complies with ethical publishing standards.
