Clinical Relevance of Biochemical Liver Markers in RNA Virus-Induced Chronic Liver Disease
DOI:
https://doi.org/10.66238/jaeee12Keywords:
Chronic Liver Disease, RNA Viruses, Hepatitis C, Liver Function Tests, ALTAbstract
RNA virus-induced chronic liver diseases, primarily caused by Hepatitis C Virus (HCV) and Hepatitis E Virus (HEV), continue to afflict millions globally and pose a significant clinical burden in South Asia. This study explores the clinical relevance of key biochemical liver markers—ALT, AST, ALP, bilirubin, and albumin—in diagnosing and managing chronic liver disease (CLD). A cross-sectional analysis of 250 patients with confirmed RNA-virus-induced CLD was conducted. Findings demonstrate a consistent elevation in ALT, AST, and ALP, along with hypoalbuminemia and hyperbilirubinemia, reflecting ongoing hepatocellular damage and reduced hepatic synthetic function. Understanding these biochemical shifts is crucial for early diagnosis, therapeutic decisions, and patient monitoring, especially in resource-limited settings.
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Copyright (c) 2025 Nadia S. Qureshi, Nadia S. Qureshi
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